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KMID : 0616120070380010019
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Korean Journal of Pharmacognosy
2007 Volume.38 No. 1 p.19 ~ p.21
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Isolation and Quantitative Determination Method Validation of myristicin from Myristica fragrans Houttuyn
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Kim Su-Hwan
Lee Dong-Ho
Kwun Soo-Han
Lim Byeong-ho
Lee Sang-Hoon
Min Bum-Chan
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Abstract
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Myristica fragrans has been used for the treatment of stomachache in East Asia. It is very important to determine the amount of myristicin in Myristica fragrans, because excess myristicin causes side effects. In this study, we developed and validated the method for determination contents of myristicin in Myristica fragrans which was purchased from various regions of Korea. The average content of myristicin in Myristica fragrans was 2.10% with the validated HPLC analysis method.
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KEYWORD
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Myristicin, Myristica fragrans, quantitative analysis, validation
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